|
Allele Symbol Allele Name Allele ID |
Snrktm1Hxu targeted mutation 1, Haiyan Xu MGI:6147677 |
||||||||||||
| Summary |
2 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• decreased blood glucose levels
|
|
• pups die by postnatal day 2
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• white adipose tissue (WAT) is decreased by 50% in subcutaneous tissue
|
|
• white adipose tissue (WAT) is decreased by 40% in epididymal tissue and 50% in subcutaneous tissue
|
|
• mitochondria density in BAT is decreased and has occasional ruptures of mitochondrial cristae
|
|
• brown adipose tissue (BAT) mass is decreased by 33% and have with less lipid accumulation
|
|
• crown-like structure found in WAT
|
|
• body weight in males is similar to wild-type at 4 weeks, but decreases by 22 weeks
|
|
• on high fat diet, mice exhibit higher fasting blood glucose levels, however, there are no differences in body or fat pad weight
|
|
• triglyceride contents of epididymal and subcutaneous WAT is decreased
|
|
• white adipose tissue (WAT) is decreased by 50% in subcutaneous tissue
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 06/12/2024 MGI 6.13 |
|
|
|
||
Analysis Tools