Phenotypes associated with this allele

• Allele Symbol: Cand1^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6149007
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cand1^em1(IMPC)Mbp/Cand1^em1(IMPC)Mbp	C57BL/6NCrl-Cand1^em1(IMPC)Mbp/Mmucd	MGI:6288369
ht2	Cand1^em1(IMPC)Mbp/Cand1^+	C57BL/6NCrl-Cand1^em1(IMPC)Mbp/Mmucd	MGI:6262030

Genotype
MGI:6288369

hm1

• Allelic Composition: Cand1^em1(IMPC)Mbp/Cand1^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Cand1^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Cand1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6262030

ht2

• Allelic Composition: Cand1^em1(IMPC)Mbp/Cand1⁺
• Genetic Background: C57BL/6NCrl-Cand1^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Cand1

cardiovascular system

abnormal heart morphology ( J:211773 )

♀

IMPC - UCD

small heart ( J:211773 )

♀

IMPC - UCD

decreased heart rate ( J:211773 )

♂

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal gallbladder morphology ( J:211773 )

♀

IMPC - UCD

enlarged gallbladder ( J:211773 )

♀

IMPC - UCD

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

small testis ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged gallbladder ( J:211773 )

♀

IMPC - UCD

enlarged liver ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♂

IMPC - UCD

edema ( J:211773 )

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

♀

IMPC - UCD

enlarged lymph nodes ( J:211773 )

♀

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - UCD

liver/biliary system

abnormal gallbladder morphology ( J:211773 )

♀

IMPC - UCD

enlarged gallbladder ( J:211773 )

♀

IMPC - UCD

enlarged liver ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD

small kidney ( J:211773 )

♀

IMPC - UCD

reproductive system

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

small testis ( J:211773 )

♂

IMPC - UCD

abnormal uterus morphology ( J:211773 )

♀

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD