All Phenotypes Chmp2b<em1(IMPC)Mbp> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Chmp2b^em1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6149048

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Chmp2b^em1(IMPC)Mbp/Chmp2b^em1(IMPC)Mbp	C57BL/6NCrl-Chmp2b^em1(IMPC)Mbp/MbpMmucd	MGI:7471937
hm2	Chmp2b^em1(IMPC)Mbp/Chmp2b^em1(IMPC)Mbp	C57BL/6NCrl-Chmp2b^em1(IMPC)Mbp/Mmucd	MGI:6288393
ht3	Chmp2b^em1(IMPC)Mbp/Chmp2b⁺	C57BL/6NCrl-Chmp2b^em1(IMPC)Mbp/MbpMmucd	MGI:7471936
ht4	Chmp2b^em1(IMPC)Mbp/Chmp2b⁺	C57BL/6NCrl-Chmp2b^em1(IMPC)Mbp/Mmucd	MGI:6370392

Allelic Composition	Chmp2b^em1(IMPC)Mbp/Chmp2b^em1(IMPC)Mbp
Genetic Background	C57BL/6NCrl-Chmp2b^em1(IMPC)Mbp/MbpMmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chmp2b^em1(IMPC)Mbp mutation (1 available); any Chmp2b mutation (24 available)

Data Sources

IMPC Data for Chmp2b

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

Allelic Composition	Chmp2b^em1(IMPC)Mbp/Chmp2b^em1(IMPC)Mbp
Genetic Background	C57BL/6NCrl-Chmp2b^em1(IMPC)Mbp/Mmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chmp2b^em1(IMPC)Mbp mutation (1 available); any Chmp2b mutation (24 available)

Data Sources

IMPC Data for Chmp2b

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

Allelic Composition	Chmp2b^em1(IMPC)Mbp/Chmp2b⁺
Genetic Background	C57BL/6NCrl-Chmp2b^em1(IMPC)Mbp/MbpMmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chmp2b^em1(IMPC)Mbp mutation (1 available); any Chmp2b mutation (24 available)

Data Sources

IMPC Data for Chmp2b

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

Allelic Composition	Chmp2b^em1(IMPC)Mbp/Chmp2b⁺
Genetic Background	C57BL/6NCrl-Chmp2b^em1(IMPC)Mbp/Mmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chmp2b^em1(IMPC)Mbp mutation (1 available); any Chmp2b mutation (24 available)

Data Sources

IMPC Data for Chmp2b

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

decreased heart rate ( J:211773 )

IMPC - UCD

prolonged RR interval ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

enlarged seminal vesicle ( J:211773 )

IMPC - UCD

absent seminal vesicle ( J:211773 )

IMPC - UCD

abnormal testis morphology ( J:211773 )

IMPC - UCD

small testis ( J:211773 )

IMPC - UCD

growth/size/body

enlarged spleen ( J:211773 )

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

IMPC - UCD

small kidney ( J:211773 )

IMPC - UCD

reproductive system

enlarged seminal vesicle ( J:211773 )

IMPC - UCD

absent seminal vesicle ( J:211773 )

IMPC - UCD

abnormal testis morphology ( J:211773 )

IMPC - UCD

small testis ( J:211773 )

IMPC - UCD

abnormal uterus morphology ( J:211773 )

IMPC - UCD

blind uterus ( J:211773 )

IMPC - UCD

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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