Phenotypes associated with this allele

• Allele Symbol: Tg(Mnx1-Zfp106,-EGFP)2Blk
• Allele Name: transgene insertion 2, Brian L Black
• Allele ID: MGI:6150003
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(Mnx1-Zfp106,-EGFP)2Blk/0 Zfp106^tm1b(KOMP)Wtsi/Zfp106^tm1b(KOMP)Wtsi	involves: C57BL/6N	MGI:6150434

Genotype
MGI:6150434

cx1

• Allelic Composition: Tg(Mnx1-Zfp106,-EGFP)2Blk/0; Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi}
• Genetic Background: involves: C57BL/6N
• Cell Lines: EPD0033_4_C03

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal muscle fiber morphology ( J:241305 )

• significant suppression of muscle wasting compared to Zfp106 knockout allele alone

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:241305 )

• significant suppression of muscle wasting and of loss of grip strength compared to Zfp106 knockout allele alone

nervous system

abnormal motor neuron morphology ( J:241305 )

• significant restoration of number of choline-acetyltransferase-positive motor neurons in spinal cord compared to Zfp106 knockout allele alone

growth/size/body

abnormal body weight ( J:241305 )

• significant suppression of muscle wasting compared to Zfp106 knockout allele alone