About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gpr37l1tm1d(EUCOMM)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:6150820
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gpr37l1tm1d(EUCOMM)Wtsi/Gpr37l1tm1d(EUCOMM)Wtsi involves: BALB/cJ * C57BL/6N * SJL MGI:6151045
ht2
Gpr37l1tm1d(EUCOMM)Wtsi/Gpr37l1+ involves: BALB/cJ * C57BL/6N * SJL MGI:6151046


Genotype
MGI:6151045
hm1
Allelic
Composition
Gpr37l1tm1d(EUCOMM)Wtsi/Gpr37l1tm1d(EUCOMM)Wtsi
Genetic
Background
involves: BALB/cJ * C57BL/6N * SJL
Cell Lines EPD0486_2_B09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpr37l1tm1d(EUCOMM)Wtsi mutation (1 available); any Gpr37l1 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
N
• anesthetized female mice exhibit normal left ventricular systolic pressure, end-diastolic pressure and dP/dT max or min
• in anesthetized female mice
• in anesthetized female mice
• in female mice whether anesthetized or conscious
• in female mice whether anesthetized or conscious

homeostasis/metabolism
• female and male mice exhibit protection from AngII-induced cardiac fibrosis compared with wild-type mice
• male mice exhibit increased AngII-induced left ventricular hypertrophy and pulmonary edema resulting from congestive heart failure compared with wild-type mice
• however, female mice exhibit AngII-induced hypertension




Genotype
MGI:6151046
ht2
Allelic
Composition
Gpr37l1tm1d(EUCOMM)Wtsi/Gpr37l1+
Genetic
Background
involves: BALB/cJ * C57BL/6N * SJL
Cell Lines EPD0486_2_B09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpr37l1tm1d(EUCOMM)Wtsi mutation (1 available); any Gpr37l1 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory