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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccdc186em1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6152423
Summary 4 genotypes


Genotype
MGI:7471921
hm1
Allelic
Composition		 Ccdc186em1(IMPC)Mbp/Ccdc186em1(IMPC)Mbp
Genetic
Background		 C57BL/6NCrl-Ccdc186em1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccdc186em1(IMPC)Mbp mutation (1 available); any Ccdc186 mutation (36 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial

embryo

growth/size/body
embryonic growth retardation ( J:211773 )
IMPC - UCD

homeostasis/metabolism
edema ( J:211773 )
IMPC - UCD

vision/eye
microphthalmia ( J:211773 )
IMPC - UCD




Genotype
MGI:6288376
hm2
Allelic
Composition		 Ccdc186em1(IMPC)Mbp/Ccdc186em1(IMPC)Mbp
Genetic
Background		 C57BL/6NCrl-Ccdc186em1(IMPC)Mbp/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccdc186em1(IMPC)Mbp mutation (1 available); any Ccdc186 mutation (36 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
hemorrhage ( J:211773 )
IMPC - UCD

mortality/aging




Genotype
MGI:7471920
ht3
Allelic
Composition		 Ccdc186em1(IMPC)Mbp/Ccdc186+
Genetic
Background		 C57BL/6NCrl-Ccdc186em1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccdc186em1(IMPC)Mbp mutation (1 available); any Ccdc186 mutation (36 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo

vision/eye
microphthalmia ( J:211773 )
IMPC - UCD




Genotype
MGI:6461128
ht4
Allelic
Composition		 Ccdc186em1(IMPC)Mbp/Ccdc186+
Genetic
Background		 C57BL/6NCrl-Ccdc186em1(IMPC)Mbp/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccdc186em1(IMPC)Mbp mutation (1 available); any Ccdc186 mutation (36 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
hemorrhage ( J:211773 )
IMPC - UCD

vision/eye




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory