Phenotypes associated with this allele

• Allele Symbol: Ddx6^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6152458
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ddx6^em1(IMPC)Mbp/Ddx6^em1(IMPC)Mbp	C57BL/6N-Ddx6^em1(IMPC)Mbp/Ucd	MGI:6262271
ht2	Ddx6^em1(IMPC)Mbp/Ddx6^+	C57BL/6N-Ddx6^em1(IMPC)Mbp/Ucd	MGI:6288417

Genotype
MGI:6262271

hm1

• Allelic Composition: Ddx6^em1(IMPC)Mbp/Ddx6^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Ddx6^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Ddx6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo turning ( J:211773 )

IMPC - UCD

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - UCD

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - UCD

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6288417

ht2

• Allelic Composition: Ddx6^em1(IMPC)Mbp/Ddx6⁺
• Genetic Background: C57BL/6N-Ddx6^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Ddx6

behavior/neurological

decreased startle reflex ( J:211773 )

IMPC - UCD

embryo

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - UCD

increased mean corpuscular volume ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

increased circulating total protein level ( J:211773 )

♀

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♂

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

♂

IMPC - UCD

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD