Phenotypes associated with this allele

• Allele Symbol: Faf2^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6152475
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Faf2^em1(IMPC)Mbp/Faf2^em1(IMPC)Mbp	C57BL/6N-Faf2^em1(IMPC)Mbp/Ucd	MGI:6288456
ht2	Faf2^em1(IMPC)Mbp/Faf2^+	C57BL/6N-Faf2^em1(IMPC)Mbp/Ucd	MGI:6262402

Genotype
MGI:6288456

hm1

• Allelic Composition: Faf2^em1(IMPC)Mbp/Faf2^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Faf2^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Faf2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

abnormal vitelline vasculature morphology ( J:211773 )

♂

IMPC - UCD

abnormal heart morphology ( J:211773 )

IMPC - UCD

hemorrhage ( J:211773 )

IMPC - UCD

craniofacial

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - UCD

embryo

abnormal vitelline vasculature morphology ( J:211773 )

♂

IMPC - UCD

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - UCD

abnormal embryo turning ( J:211773 )

IMPC - UCD

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

abnormal neural tube closure ( J:211773 )

IMPC - UCD

abnormal allantois morphology ( J:211773 )

♀

IMPC - UCD

abnormal visceral yolk sac morphology ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

abnormal neural tube closure ( J:211773 )

IMPC - UCD

abnormal forebrain development ( J:211773 )

IMPC - UCD

abnormal hindbrain development ( J:211773 )

IMPC - UCD

abnormal midbrain development ( J:211773 )

IMPC - UCD

vision/eye

abnormal optic vesicle formation ( J:211773 )

IMPC - UCD

Genotype
MGI:6262402

ht2

• Allelic Composition: Faf2^em1(IMPC)Mbp/Faf2⁺
• Genetic Background: C57BL/6N-Faf2^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Faf2

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

♀

IMPC - UCD

abnormal neural tube morphology ( J:211773 )

♀

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

nervous system

abnormal neural tube morphology ( J:211773 )

♀

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

♀

IMPC - UCD