Phenotypes associated with this allele

• Allele Symbol: Larp1^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6152506
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Larp1^em1(IMPC)Mbp/Larp1^em1(IMPC)Mbp	C57BL/6N-Larp1^em1(IMPC)Mbp/Ucd	MGI:6288547
ht2	Larp1^em1(IMPC)Mbp/Larp1^+	C57BL/6N-Larp1^em1(IMPC)Mbp/Ucd	MGI:6461399

Genotype
MGI:6288547

hm1

• Allelic Composition: Larp1^em1(IMPC)Mbp/Larp1^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Larp1^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Larp1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal head shape ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

growth/size/body

abnormal head shape ( J:211773 )

IMPC - UCD

embryonic growth retardation ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6461399

ht2

• Allelic Composition: Larp1^em1(IMPC)Mbp/Larp1⁺
• Genetic Background: C57BL/6N-Larp1^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Larp1

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - UCD

enlarged heart ( J:211773 )

♂

IMPC - UCD

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

small testis ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

enlarged urinary bladder ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

hematopoietic system

increased mean platelet volume ( J:211773 )

♂

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - UCD

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

♂

IMPC - UCD

renal/urinary system

enlarged kidney ( J:211773 )

♂

IMPC - UCD

enlarged urinary bladder ( J:211773 )

♂

IMPC - UCD

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

small testis ( J:211773 )

♂

IMPC - UCD