Phenotypes associated with this allele

• Allele Symbol: Lmod3^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6152507
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lmod3^em1(IMPC)Mbp/Lmod3^em1(IMPC)Mbp	C57BL/6N-Lmod3^em1(IMPC)Mbp/Ucd	MGI:6262806
ht2	Lmod3^em1(IMPC)Mbp/Lmod3^+	C57BL/6N-Lmod3^em1(IMPC)Mbp/Ucd	MGI:6480493

Genotype
MGI:6262806

hm1

• Allelic Composition: Lmod3^em1(IMPC)Mbp/Lmod3^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Lmod3^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Lmod3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - UCD

increased total body fat amount ( J:211773 )

IMPC - UCD

behavior/neurological

abnormal startle reflex ( J:211773 )

IMPC - UCD

decreased startle reflex ( J:211773 )

IMPC - UCD

decreased grip strength ( J:211773 )

IMPC - UCD

decreased locomotor activity ( J:211773 )

♀

IMPC - UCD

no spontaneous movement ( J:211773 )

IMPC - UCD

abnormal vocalization ( J:211773 )

♂

IMPC - UCD

cardiovascular system

enlarged heart ( J:211773 )

♂

IMPC - UCD

decreased heart rate ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

enlarged thymus ( J:211773 )

♀

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

decreased lean body mass ( J:211773 )

IMPC - UCD

increased lean body mass ( J:211773 )

♂

IMPC - UCD

decreased body length ( J:211773 )

♀

IMPC - UCD

enlarged urinary bladder ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

hematopoietic system

enlarged thymus ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

increased neutrophil cell number ( J:211773 )

♂

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

increased circulating insulin level ( J:211773 )

IMPC - UCD

improved glucose tolerance ( J:211773 )

♂

IMPC - UCD

abnormal cholesterol homeostasis ( J:211773 )

IMPC - UCD

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - UCD

immune system

enlarged thymus ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

increased neutrophil cell number ( J:211773 )

♂

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - UCD

enlarged lymph nodes ( J:211773 )

♂

IMPC - UCD

muscle

abnormal skeletal muscle morphology ( J:211773 )

IMPC - UCD

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal urinary bladder morphology ( J:211773 )

♂

IMPC - UCD

enlarged urinary bladder ( J:211773 )

♂

IMPC - UCD

skeleton

decreased bone mineral content ( J:211773 )

IMPC - UCD

decreased bone mineral density ( J:211773 )

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♂

IMPC - UCD

Genotype
MGI:6480493

ht2

• Allelic Composition: Lmod3^em1(IMPC)Mbp/Lmod3⁺
• Genetic Background: C57BL/6N-Lmod3^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Lmod3

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

small heart ( J:211773 )

♀

IMPC - UCD

endocrine/exocrine glands

abnormal adrenal gland morphology ( J:211773 )

IMPC - UCD

growth/size/body

enlarged kidney ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

hematopoietic system

increased erythrocyte cell number ( J:211773 )

♀

IMPC - UCD

increased hematocrit ( J:211773 )

♀

IMPC - UCD

increased hemoglobin content ( J:211773 )

♀

IMPC - UCD

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

increased blood urea nitrogen level ( J:211773 )

♂

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

integument

abnormal coat/hair pigmentation ( J:211773 )

IMPC - UCD

abnormal skin morphology ( J:211773 )

IMPC - UCD

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD

enlarged kidney ( J:211773 )

♀

IMPC - UCD

small kidney ( J:211773 )

♀

IMPC - UCD

reproductive system

hydrometra ( J:211773 )

♀

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - UCD