Phenotypes associated with this allele

• Allele Symbol: Naa10^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6152521
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Naa10^em1(IMPC)Mbp/Naa10^em1(IMPC)Mbp	C57BL/6NCrl-Naa10^em1(IMPC)Mbp/Mmucd	MGI:6262960
ot2	Naa10^em1(IMPC)Mbp/Y	C57BL/6NCrl-Naa10^em1(IMPC)Mbp/Mmucd	MGI:6461464

Genotype
MGI:6262960

hm1

• Allelic Composition: Naa10^em1(IMPC)Mbp/Naa10^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Naa10^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Naa10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♀

IMPC - UCD

behavior/neurological

increased grip strength ( J:211773 )

♀

IMPC - UCD

cardiovascular system

abnormal heart morphology ( J:211773 )

♀

IMPC - UCD

enlarged heart ( J:211773 )

♀

IMPC - UCD

endocrine/exocrine glands

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♀

IMPC - UCD

increased lean body mass ( J:211773 )

♀

IMPC - UCD

enlarged kidney ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

decreased circulating bilirubin level ( J:211773 )

♀

IMPC - UCD

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - UCD

improved glucose tolerance ( J:211773 )

♀

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

♀

IMPC - UCD

enlarged lymph nodes ( J:211773 )

♀

IMPC - UCD

integument

abnormal coat/hair pigmentation ( J:211773 )

♀

IMPC - UCD

abnormal skin morphology ( J:211773 )

♀

IMPC - UCD

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

♀

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD

enlarged kidney ( J:211773 )

♀

IMPC - UCD

reproductive system

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

abnormal uterus morphology ( J:211773 )

♀

IMPC - UCD

hydrometra ( J:211773 )

♀

IMPC - UCD

respiratory system

abnormal trachea morphology ( J:211773 )

♀

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - UCD

microphthalmia ( J:211773 )

♀

IMPC - UCD

Genotype
MGI:6461464

ot2

• Allelic Composition: Naa10^em1(IMPC)Mbp/Y
• Genetic Background: C57BL/6NCrl-Naa10^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Naa10

cardiovascular system

decreased heart weight ( J:211773 )

♂

IMPC - UCD

endocrine/exocrine glands

abnormal adrenal gland morphology ( J:211773 )

♂

IMPC - UCD

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

small testis ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged kidney ( J:211773 )

♂

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

♂

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

♂

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

♂

IMPC - UCD

enlarged lymph nodes ( J:211773 )

♂

IMPC - UCD

integument

abnormal coat/hair pigmentation ( J:211773 )

♂

IMPC - UCD

abnormal skin morphology ( J:211773 )

♂

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

♂

IMPC - UCD

nervous system

abnormal brain morphology ( J:211773 )

♂

IMPC - UCD

hydrocephaly ( J:211773 )

♂

IMPC - UCD

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

small kidney ( J:211773 )

♂

IMPC - UCD

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

small testis ( J:211773 )

♂

IMPC - UCD

enlarged epididymis ( J:211773 )

♂

IMPC - UCD