Phenotypes associated with this allele

• Allele Symbol: Ndrg3^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6152522
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ndrg3^em1(IMPC)Mbp/Ndrg3^em1(IMPC)Mbp	C57BL/6NCrl-Ndrg3^em1(IMPC)Mbp/Mmucd	MGI:6262984
ht2	Ndrg3^em1(IMPC)Mbp/Ndrg3^+	C57BL/6NCrl-Ndrg3^em1(IMPC)Mbp/Mmucd	MGI:6394335

Genotype
MGI:6262984

hm1

• Allelic Composition: Ndrg3^em1(IMPC)Mbp/Ndrg3^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Ndrg3^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Ndrg3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - UCD

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6394335

ht2

• Allelic Composition: Ndrg3^em1(IMPC)Mbp/Ndrg3⁺
• Genetic Background: C57BL/6NCrl-Ndrg3^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Ndrg3

behavior/neurological

increased freezing behavior ( J:211773 )

♂

IMPC - UCD

embryo

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

small testis ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged kidney ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

hematopoietic system

enlarged spleen ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

decreased circulating calcium level ( J:211773 )

♂

IMPC - UCD

immune system

enlarged spleen ( J:211773 )

♀

IMPC - UCD

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

renal/urinary system

enlarged kidney ( J:211773 )

♀

IMPC - UCD

reproductive system

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

small testis ( J:211773 )

♂

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - UCD