All Phenotypes Rbm22<em1(IMPC)Mbp> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rbm22^em1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6152623

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rbm22^em1(IMPC)Mbp/Rbm22^em1(IMPC)Mbp	C57BL/6NCrl-Rbm22^em1(IMPC)Mbp/Mmucd	MGI:6263333
ht2	Rbm22^em1(IMPC)Mbp/Rbm22⁺	C57BL/6NCrl-Rbm22^em1(IMPC)Mbp/Mmucd	MGI:6263332

Allelic Composition	Rbm22^em1(IMPC)Mbp/Rbm22^em1(IMPC)Mbp
Genetic Background	C57BL/6NCrl-Rbm22^em1(IMPC)Mbp/Mmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rbm22^em1(IMPC)Mbp mutation (1 available); any Rbm22 mutation (14 available)

Data Sources

IMPC Data for Rbm22

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - UCD

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - UCD

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Allelic Composition	Rbm22^em1(IMPC)Mbp/Rbm22⁺
Genetic Background	C57BL/6NCrl-Rbm22^em1(IMPC)Mbp/Mmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rbm22^em1(IMPC)Mbp mutation (1 available); any Rbm22 mutation (14 available)

Data Sources

IMPC Data for Rbm22

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - UCD

enlarged heart ( J:211773 )

IMPC - UCD

increased heart weight ( J:211773 )

IMPC - UCD

hemorrhage ( J:211773 )

IMPC - UCD

digestive/alimentary system

abnormal duodenum morphology ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal ovary morphology ( J:211773 )

IMPC - UCD

abnormal testis morphology ( J:211773 )

IMPC - UCD

small testis ( J:211773 )

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

IMPC - UCD

increased heart weight ( J:211773 )

IMPC - UCD

hematopoietic system

increased mean corpuscular hemoglobin concentration ( J:211773 )

IMPC - UCD

abnormal spleen morphology ( J:211773 )

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

IMPC - UCD

enlarged lymph nodes ( J:211773 )

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

reproductive system

abnormal ovary morphology ( J:211773 )

IMPC - UCD

abnormal testis morphology ( J:211773 )

IMPC - UCD

small testis ( J:211773 )

IMPC - UCD

abnormal uterus morphology ( J:211773 )

IMPC - UCD

abnormal epididymis morphology ( J:211773 )

IMPC - UCD

enlarged epididymis ( J:211773 )

IMPC - UCD

skeleton

abnormal lumbar vertebrae morphology ( J:211773 )

IMPC - UCD

abnormal sacral vertebrae morphology ( J:211773 )

IMPC - UCD

increased bone mineral content ( J:211773 )

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - UCD

microphthalmia ( J:211773 )

IMPC - UCD

anophthalmia ( J:211773 )

IMPC - UCD

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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