Phenotypes associated with this allele

• Allele Symbol: Tle4^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6152659
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tle4^em1(IMPC)Mbp/Tle4^em1(IMPC)Mbp	C57BL/6NCrl-Tle4^em1(IMPC)Mbp/Mmucd	MGI:6288776

Genotype
MGI:6288776

hm1

• Allelic Composition: Tle4^em1(IMPC)Mbp/Tle4^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Tle4^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Tle4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - UCD

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - UCD

decreased locomotor activity ( J:211773 )

♂

IMPC - UCD

cardiovascular system

decreased heart weight ( J:211773 )

IMPC - UCD

digestive/alimentary system

abnormal rectum morphology ( J:211773 )

♂

IMPC - UCD

growth/size/body

decreased lean body mass ( J:211773 )

IMPC - UCD

enlarged liver ( J:211773 )

♂

IMPC - UCD

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♀

IMPC - UCD

abnormal cholesterol homeostasis ( J:211773 )

IMPC - UCD

immune system

abnormal lymph node morphology ( J:211773 )

♀

IMPC - UCD

enlarged lymph nodes ( J:211773 )

♀

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♂

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - UCD

enlarged liver ( J:211773 )

♂

IMPC - UCD

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD

small kidney ( J:211773 )

♀

IMPC - UCD

reproductive system

male infertility ( J:211773 )

♂

IMPC - UCD

skeleton

decreased bone mineral content ( J:211773 )

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - UCD