All Phenotypes Wdr11<em1(IMPC)Mbp> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Wdr11^em1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6152678

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Wdr11^em1(IMPC)Mbp/Wdr11^em1(IMPC)Mbp	C57BL/6NCrl-Wdr11^em1(IMPC)Mbp/Mmucd	MGI:6263875
ht2	Wdr11^em1(IMPC)Mbp/Wdr11⁺	C57BL/6NCrl-Wdr11^em1(IMPC)Mbp/Mmucd	MGI:6263874

Allelic Composition	Wdr11^em1(IMPC)Mbp/Wdr11^em1(IMPC)Mbp
Genetic Background	C57BL/6NCrl-Wdr11^em1(IMPC)Mbp/Mmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wdr11^em1(IMPC)Mbp mutation (1 available); any Wdr11 mutation (60 available)

Data Sources

IMPC Data for Wdr11

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

absent adrenal gland ( J:211773 )

IMPC - UCD

hematopoietic system

increased red blood cell distribution width ( J:211773 )

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - UCD

reproductive system

male infertility ( J:211773 )

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - UCD

anophthalmia ( J:211773 )

IMPC - UCD

Allelic Composition	Wdr11^em1(IMPC)Mbp/Wdr11⁺
Genetic Background	C57BL/6NCrl-Wdr11^em1(IMPC)Mbp/Mmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wdr11^em1(IMPC)Mbp mutation (1 available); any Wdr11 mutation (60 available)

Data Sources

IMPC Data for Wdr11

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - UCD

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - UCD

enlarged heart ( J:211773 )

IMPC - UCD

small heart ( J:211773 )

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

IMPC - UCD

homeostasis/metabolism

improved glucose tolerance ( J:211773 )

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

IMPC - UCD

limbs/digits/tail

abnormal tail length ( J:211773 )

IMPC - UCD

nervous system

abnormal spinal cord morphology ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

IMPC - UCD

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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