Phenotypes associated with this allele

• Allele Symbol: Xpo1^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6152680
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Xpo1^em1(IMPC)Mbp/Xpo1^em1(IMPC)Mbp	C57BL/6NCrl-Xpo1^em1(IMPC)Mbp/Mmucd	MGI:6263891
ht2	Xpo1^em1(IMPC)Mbp/Xpo1^+	C57BL/6NCrl-Xpo1^em1(IMPC)Mbp/Mmucd	MGI:6480636

Genotype
MGI:6263891

hm1

• Allelic Composition: Xpo1^em1(IMPC)Mbp/Xpo1^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Xpo1^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Xpo1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - UCD

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - UCD

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6480636

ht2

• Allelic Composition: Xpo1^em1(IMPC)Mbp/Xpo1⁺
• Genetic Background: C57BL/6NCrl-Xpo1^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Xpo1

cardiovascular system

increased heart weight ( J:211773 )

IMPC - UCD

hemorrhage ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

growth/size/body

increased heart weight ( J:211773 )

IMPC - UCD

microcephaly ( J:211773 )

IMPC - UCD

limbs/digits/tail

polydactyly ( J:211773 )

IMPC - UCD

syndactyly ( J:211773 )

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD

anophthalmia ( J:211773 )

IMPC - UCD