Phenotypes associated with this allele

• Allele Symbol: Auts2^{em1(IMPC)Wtsi}
• Allele Name: endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• Allele ID: MGI:6153281
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Auts2^em1(IMPC)Wtsi/Auts2^em1(IMPC)Wtsi	C57BL/6N-Auts2^em1(IMPC)Wtsi/Wtsi	MGI:6161262
ht2	Auts2^em1(IMPC)Wtsi/Auts2^+	C57BL/6N-Auts2^em1(IMPC)Wtsi/Wtsi	MGI:6261941

Genotype
MGI:6161262

hm1

• Allelic Composition: Auts2^{em1(IMPC)Wtsi}/Auts2^{em1(IMPC)Wtsi}
• Genetic Background: C57BL/6N-Auts2^{em1(IMPC)Wtsi}/Wtsi

Data Sources

IMPC Data for Auts2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

absent segment of posterior cerebral artery ( J:239583 )

DMDD

abnormal ductus venosus valve morphology ( J:239583 )

DMDD

abnormal inferior vena cava morphology ( J:239583 )

DMDD

abnormal interatrial septum morphology ( J:239583 )

DMDD

embryo

abnormal Mullerian duct topology ( J:239583 )

DMDD

endocrine/exocrine glands

biliary cyst ( J:239583 )

DMDD

growth/size/body

biliary cyst ( J:239583 )

DMDD

liver/biliary system

biliary cyst ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

neoplasm

increased hemangioma incidence ( J:239583 )

DMDD

embryo tumor ( J:239583 )

DMDD

nervous system

absent segment of posterior cerebral artery ( J:239583 )

DMDD

abnormal hypoglossal nerve topology ( J:239583 )

DMDD

Genotype
MGI:6261941

ht2

• Allelic Composition: Auts2^{em1(IMPC)Wtsi}/Auts2⁺
• Genetic Background: C57BL/6N-Auts2^{em1(IMPC)Wtsi}/Wtsi

Data Sources

IMPC Data for Auts2

growth/size/body

increased lean body mass ( J:211773 )

IMPC - WTSI

decreased body length ( J:211773 )

♀

IMPC - WTSI