Phenotypes associated with this allele

• Allele Symbol: Irgm1^{em1(IMPC)Wtsi}
• Allele Name: endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• Allele ID: MGI:6153372
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Irgm1^em1(IMPC)Wtsi/Irgm1^em1(IMPC)Wtsi	C57BL/6N-Irgm1^em1(IMPC)Wtsi/Wtsi	MGI:6262713

Genotype
MGI:6262713

hm1

• Allelic Composition: Irgm1^{em1(IMPC)Wtsi}/Irgm1^{em1(IMPC)Wtsi}
• Genetic Background: C57BL/6N-Irgm1^{em1(IMPC)Wtsi}/Wtsi

Data Sources

IMPC Data for Irgm1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased lean body mass ( J:211773 )

♂

IMPC - WTSI

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - WTSI

decreased hematocrit ( J:211773 )

IMPC - WTSI

decreased hemoglobin content ( J:211773 )

IMPC - WTSI

increased red blood cell distribution width ( J:211773 )

IMPC - WTSI

thrombocytopenia ( J:211773 )

IMPC - WTSI

increased mean platelet volume ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

decreased circulating fructosamine level ( J:211773 )

IMPC - WTSI

decreased circulating glucose level ( J:211773 )

IMPC - WTSI

decreased fasting circulating glucose level ( J:211773 )

♂

IMPC - WTSI

increased circulating cholesterol level ( J:211773 )

♀

IMPC - WTSI

increased circulating LDL cholesterol level ( J:211773 )

♀

IMPC - WTSI

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - WTSI

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - WTSI

decreased circulating serum albumin level ( J:211773 )

♂

IMPC - WTSI

improved glucose tolerance ( J:211773 )

♂

IMPC - WTSI

vision/eye

abnormal eye morphology ( J:211773 )

♂

IMPC - WTSI