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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc22a12tm1Oka
targeted mutation 1, Masaru Okabe
MGI:6153680
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc22a12tm1Oka/Slc22a12tm1Oka involves: 129 * C57BL/6J MGI:6154213


Genotype
MGI:6154213
hm1
Allelic
Composition		 Slc22a12tm1Oka/Slc22a12tm1Oka
Genetic
Background		 involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc22a12tm1Oka mutation (0 available); any Slc22a12 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased urine uric acid level ( J:260689 )
• increase in the amount of urinary urate excretion
• however, plasma levels of urate are normal

renal/urinary system
increased urine uric acid level ( J:260689 )
• increase in the amount of urinary urate excretion
• however, plasma levels of urate are normal
abnormal renal reabsorption ( J:260689 )
• decrease in the urinary allantoin/urate ratio, indicating an attenuated renal reabsorption of urate and decreased allantoin production from reabsorbed urate




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory