Phenotypes associated with this allele

• Allele Symbol: Herc1^{em3(IMPC)Wtsi}
• Allele Name: endonuclease-mediated mutation 3, Wellcome Trust Sanger Institute
• Allele ID: MGI:6153732
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Herc1^em3(IMPC)Wtsi/Herc1^em3(IMPC)Wtsi	C57BL/6N-Herc1^em3(IMPC)Wtsi/Wtsi	MGI:6262615

Genotype
MGI:6262615

hm1

• Allelic Composition: Herc1^{em3(IMPC)Wtsi}/Herc1^{em3(IMPC)Wtsi}
• Genetic Background: C57BL/6N-Herc1^{em3(IMPC)Wtsi}/Wtsi

Data Sources

IMPC Data for Herc1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - WTSI

growth/size/body

decreased lean body mass ( J:211773 )

IMPC - WTSI

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - WTSI

hematopoietic system

increased red blood cell distribution width ( J:211773 )

IMPC - WTSI

increased mean platelet volume ( J:211773 )

IMPC - WTSI

increased leukocyte cell number ( J:211773 )

♀

IMPC - WTSI

increased eosinophil cell number ( J:211773 )

♀

IMPC - WTSI

increased monocyte cell number ( J:211773 )

♀

IMPC - WTSI

increased Ly6C high monocyte number ( J:211773 )

♀

IMPC - WTSI

increased Ly6C low monocyte number ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - WTSI

decreased circulating glucose level ( J:211773 )

IMPC - WTSI

increased circulating insulin level ( J:211773 )

♂

IMPC - WTSI

increased circulating sodium level ( J:211773 )

IMPC - WTSI

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - WTSI

increased circulating amylase level ( J:211773 )

♀

IMPC - WTSI

impaired glucose tolerance ( J:211773 )

♂

IMPC - WTSI

increased circulating chloride level ( J:211773 )

IMPC - WTSI

immune system

increased leukocyte cell number ( J:211773 )

♀

IMPC - WTSI

increased eosinophil cell number ( J:211773 )

♀

IMPC - WTSI

increased monocyte cell number ( J:211773 )

♀

IMPC - WTSI

increased Ly6C high monocyte number ( J:211773 )

♀

IMPC - WTSI

increased Ly6C low monocyte number ( J:211773 )

IMPC - WTSI

reproductive system

male infertility ( J:211773 )

♂

IMPC - WTSI

skeleton

decreased bone mineral content ( J:211773 )

IMPC - WTSI

decreased bone mineral density ( J:211773 )

IMPC - WTSI

vision/eye

abnormal retina morphology ( J:211773 )

♀

IMPC - WTSI