Phenotypes associated with this allele

• Allele Symbol: Lats1^em1(IMPC)H
• Allele Name: endonuclease-mediated mutation 1, Harwell
• Allele ID: MGI:6153801
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lats1^em1(IMPC)H/Lats1^em1(IMPC)H	C57BL/6NTac-Lats1^em1(IMPC)H/H	MGI:6408479
ht2	Lats1^em1(IMPC)H/Lats1^+	C57BL/6NTac-Lats1^em1(IMPC)H/H	MGI:6408478

Genotype
MGI:6408479

hm1

• Allelic Composition: Lats1^em1(IMPC)H/Lats1^em1(IMPC)H
• Genetic Background: C57BL/6NTac-Lats1^em1(IMPC)H/H

Data Sources

IMPC Data for Lats1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased grip strength ( J:211773 )

♀

IMPC - HAR

decreased locomotor activity ( J:211773 )

IMPC - HAR

hematopoietic system

decreased hemoglobin content ( J:211773 )

♀

IMPC - HAR

increased neutrophil cell number ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

♀

IMPC - HAR

immune system

increased neutrophil cell number ( J:211773 )

IMPC - HAR

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - HAR

Genotype
MGI:6408478

ht2

• Allelic Composition: Lats1^em1(IMPC)H/Lats1⁺
• Genetic Background: C57BL/6NTac-Lats1^em1(IMPC)H/H

Data Sources

IMPC Data for Lats1

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - HAR