Phenotypes associated with this allele

• Allele Symbol: Spata13^em1(IMPC)H
• Allele Name: endonuclease-mediated mutation 1, Harwell
• Allele ID: MGI:6153824
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Spata13^em1(IMPC)H/Spata13^em1(IMPC)H	C57BL/6NTac-Spata13^em1(IMPC)H/H	MGI:6305794

Genotype
MGI:6305794

hm1

• Allelic Composition: Spata13^em1(IMPC)H/Spata13^em1(IMPC)H
• Genetic Background: C57BL/6NTac-Spata13^em1(IMPC)H/H

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:274791 )

N • homozygous mice do not exhibit differences in memory, anxiety, nociception compared to controls

abnormal behavior ( J:274791 )

abnormal locomotor activation ( J:274791 )

♀ • female homozygous mice show a significant elevation in activity in the first seven hours of the dark phase of the light-dark cycle compared to controls

abnormal social/conspecific interaction behavior ( J:274791 )

• homozygous mice are submissive to controls in social dominance tests

nervous system

nervous system phenotype ( J:274791 )

N • the number of glutamatergic dendritic spines on prefrontal cortex neurons was unaffected in homozygous mice