Phenotypes associated with this allele

• Allele Symbol: Psmc5^tm1.1Itl
• Allele Name: targeted mutation 1.1, inGenious Targeting Laboratory
• Allele ID: MGI:6155608
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Psmc5^tm1.1Itl/Psmc5^tm1.1Itl	involves: 129S6/SvEvTac * C57BL/6NTac	MGI:6155609

Genotype
MGI:6155609

hm1

• Allelic Composition: Psmc5^tm1.1Itl/Psmc5^tm1.1Itl
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired behavioral response to cocaine ( J:260973 )

• upon multiple sessions, cocaine-exposed mice fail to exhibit an increase in locomotor activity unlike wild-type mice

• however, mice exhibit normal habituation and acute response to cocaine exposure

abnormal sensitization to xenobiotic ( J:260973 )

• upon multiple sessions, cocaine-exposed mice fail to exhibit an increase in locomotor activity unlike wild-type mice

• however, mice exhibit normal habituation and acute response to cocaine exposure