All Phenotypes Upf3b<em1(IMPC)Tcp> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Upf3b^em1(IMPC)Tcp
endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI:6156436

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Upf3b^em1(IMPC)Tcp/Upf3b^em1(IMPC)Tcp	C57BL/6NCrl-Upf3b^em1(IMPC)Tcp/Tcp	MGI:6263828
ot2	Upf3b^em1(IMPC)Tcp/Y	C57BL/6NCrl-Upf3b^em1(IMPC)Tcp/Tcp	MGI:6263827

Allelic Composition	Upf3b^em1(IMPC)Tcp/Upf3b^em1(IMPC)Tcp
Genetic Background	C57BL/6NCrl-Upf3b^em1(IMPC)Tcp/Tcp

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Upf3b^em1(IMPC)Tcp mutation (2 available); any Upf3b mutation (13 available)

Data Sources

IMPC Data for Upf3b

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased freezing behavior ( J:211773 )

IMPC - TCP

hyperactivity ( J:211773 )

IMPC - TCP

increased vertical activity ( J:211773 )

IMPC - TCP

digestive/alimentary system

abnormal stomach morphology ( J:211773 )

IMPC - TCP

endocrine/exocrine glands

small thymus ( J:211773 )

IMPC - TCP

hematopoietic system

small thymus ( J:211773 )

IMPC - TCP

increased neutrophil cell number ( J:211773 )

IMPC - TCP

decreased lymphocyte cell number ( J:211773 )

IMPC - TCP

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - TCP

immune system

small thymus ( J:211773 )

IMPC - TCP

increased neutrophil cell number ( J:211773 )

IMPC - TCP

decreased lymphocyte cell number ( J:211773 )

IMPC - TCP

Allelic Composition	Upf3b^em1(IMPC)Tcp/Y
Genetic Background	C57BL/6NCrl-Upf3b^em1(IMPC)Tcp/Tcp

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Upf3b^em1(IMPC)Tcp mutation (2 available); any Upf3b mutation (13 available)

Data Sources

IMPC Data for Upf3b

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

hyperactivity ( J:211773 )

IMPC - TCP

endocrine/exocrine glands

small thymus ( J:211773 )

IMPC - TCP

hematopoietic system

small thymus ( J:211773 )

IMPC - TCP

decreased leukocyte cell number ( J:211773 )

IMPC - TCP

decreased lymphocyte cell number ( J:211773 )

IMPC - TCP

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - TCP

immune system

small thymus ( J:211773 )

IMPC - TCP

decreased leukocyte cell number ( J:211773 )

IMPC - TCP

decreased lymphocyte cell number ( J:211773 )

IMPC - TCP

renal/urinary system

small kidney ( J:211773 )

IMPC - TCP

skeleton

abnormal sternum morphology ( J:211773 )

IMPC - TCP

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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