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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hsd17b4em1(IMPC)Tcp
endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI:6156445
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hsd17b4em1(IMPC)Tcp/Hsd17b4em1(IMPC)Tcp C57BL/6NCrl-Hsd17b4em1(IMPC)Tcp/Tcp MGI:6262652
ht2
 		Hsd17b4em1(IMPC)Tcp/Hsd17b4+ C57BL/6NCrl-Hsd17b4em1(IMPC)Tcp/Tcp MGI:6461341


Genotype
MGI:6262652
hm1
Allelic
Composition		 Hsd17b4em1(IMPC)Tcp/Hsd17b4em1(IMPC)Tcp
Genetic
Background		 C57BL/6NCrl-Hsd17b4em1(IMPC)Tcp/Tcp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hsd17b4em1(IMPC)Tcp mutation (2 available); any Hsd17b4 mutation (50 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
limb grasping ( J:211773 )
IMPC - TCP
abnormal gait ( J:211773 )
IMPC - TCP

craniofacial

embryo

endocrine/exocrine glands

growth/size/body
abnormal tooth morphology ( J:211773 )
IMPC - TCP
abnormal embryo size ( J:211773 )
IMPC - TCP

hearing/vestibular/ear

hematopoietic system

immune system

mortality/aging

reproductive system
small uterus ( J:211773 )
IMPC - TCP

skeleton

vision/eye
cataract ( J:211773 )
IMPC - TCP




Genotype
MGI:6461341
ht2
Allelic
Composition		 Hsd17b4em1(IMPC)Tcp/Hsd17b4+
Genetic
Background		 C57BL/6NCrl-Hsd17b4em1(IMPC)Tcp/Tcp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hsd17b4em1(IMPC)Tcp mutation (2 available); any Hsd17b4 mutation (50 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

cardiovascular system
enlarged heart ( J:211773 )
IMPC - TCP

endocrine/exocrine glands

growth/size/body
enlarged heart ( J:211773 )
IMPC - TCP
enlarged urinary bladder ( J:211773 )
IMPC - TCP

homeostasis/metabolism

renal/urinary system

reproductive system
small uterus ( J:211773 )
IMPC - TCP




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory