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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tmem209em1(IMPC)Tcp
endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI:6156490
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tmem209em1(IMPC)Tcp/Tmem209em1(IMPC)Tcp C57BL/6NCrl-Tmem209em1(IMPC)Tcp/Tcp MGI:6263716
ht2
 		Tmem209em1(IMPC)Tcp/Tmem209+ C57BL/6NCrl-Tmem209em1(IMPC)Tcp/Tcp MGI:6263715


Genotype
MGI:6263716
hm1
Allelic
Composition		 Tmem209em1(IMPC)Tcp/Tmem209em1(IMPC)Tcp
Genetic
Background		 C57BL/6NCrl-Tmem209em1(IMPC)Tcp/Tcp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmem209em1(IMPC)Tcp mutation (1 available); any Tmem209 mutation (48 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial

digestive/alimentary system

embryo

growth/size/body
protruding tongue ( J:211773 )
IMPC - TCP
abnormal head shape ( J:211773 )
IMPC - TCP
abnormal embryo size ( J:211773 )
IMPC - TCP
abnormal head size ( J:211773 )
IMPC - TCP

integument
pallor ( J:211773 )
IMPC - TCP

mortality/aging

nervous system
exencephaly ( J:211773 )
IMPC - TCP

reproductive system
male infertility ( J:211773 )
IMPC - TCP

vision/eye
microphthalmia ( J:211773 )
IMPC - TCP
anophthalmia ( J:211773 )
IMPC - TCP




Genotype
MGI:6263715
ht2
Allelic
Composition		 Tmem209em1(IMPC)Tcp/Tmem209+
Genetic
Background		 C57BL/6NCrl-Tmem209em1(IMPC)Tcp/Tcp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmem209em1(IMPC)Tcp mutation (1 available); any Tmem209 mutation (48 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system

embryo

endocrine/exocrine glands

growth/size/body
abnormal embryo size ( J:211773 )
IMPC - TCP
enlarged spleen ( J:211773 )
IMPC - TCP

hematopoietic system
enlarged spleen ( J:211773 )
IMPC - TCP

immune system
enlarged spleen ( J:211773 )
IMPC - TCP

reproductive system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory