Phenotypes associated with this allele

• Allele Symbol: Nexmif^em1(IMPC)Tcp
• Allele Name: endonuclease-mediated mutation 1, The Centre for Phenogenomics
• Allele ID: MGI:6156555
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nexmif^em1(IMPC)Tcp/Nexmif^em1(IMPC)Tcp	C57BL/6N-Nexmif^em1(IMPC)Tcp/Tcp	MGI:6492977
ht2	Nexmif^em1(IMPC)Tcp/Nexmif^+	C57BL/6N-Nexmif^em1(IMPC)Tcp/Tcp	MGI:6682159
ot3	Nexmif^em1(IMPC)Tcp/Y	C57BL/6N-Nexmif^em1(IMPC)Tcp/Tcp	MGI:6408531

Genotype
MGI:6492977

hm1

• Allelic Composition: Nexmif^em1(IMPC)Tcp/Nexmif^em1(IMPC)Tcp
• Genetic Background: C57BL/6N-Nexmif^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Nexmif

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

male infertility ( J:211773 )

♂

IMPC - TCP

Genotype
MGI:6682159

ht2

• Allelic Composition: Nexmif^em1(IMPC)Tcp/Nexmif⁺
• Genetic Background: C57BL/6N-Nexmif^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Nexmif

behavior/neurological

hyperactivity ( J:211773 )

♀

IMPC - TCP

hematopoietic system

increased neutrophil cell number ( J:211773 )

♀

IMPC - TCP

immune system

increased neutrophil cell number ( J:211773 )

♀

IMPC - TCP

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - TCP

renal/urinary system

small kidney ( J:211773 )

♀

IMPC - TCP

skeleton

abnormal sternum morphology ( J:211773 )

♀

IMPC - TCP

Genotype
MGI:6408531

ot3

• Allelic Composition: Nexmif^em1(IMPC)Tcp/Y
• Genetic Background: C57BL/6N-Nexmif^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Nexmif

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - TCP

behavior/neurological

impaired contextual conditioning behavior ( J:211773 )

♂

IMPC - TCP

hyperactivity ( J:211773 )

♂

IMPC - TCP

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - TCP

decreased body length ( J:211773 )

♂

IMPC - TCP

enlarged urinary bladder ( J:211773 )

♂

IMPC - TCP

hematopoietic system

increased basophil cell number ( J:211773 )

♂

IMPC - TCP

increased eosinophil cell number ( J:211773 )

♂

IMPC - TCP

increased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - TCP

increased mean corpuscular volume ( J:211773 )

♂

IMPC - TCP

increased red blood cell distribution width ( J:211773 )

♂

IMPC - TCP

increased monocyte cell number ( J:211773 )

♂

IMPC - TCP

small spleen ( J:211773 )

♂

IMPC - TCP

homeostasis/metabolism

increased blood urea nitrogen level ( J:211773 )

♂

IMPC - TCP

increased circulating triglyceride level ( J:211773 )

♂

IMPC - TCP

immune system

increased basophil cell number ( J:211773 )

♂

IMPC - TCP

increased eosinophil cell number ( J:211773 )

♂

IMPC - TCP

increased monocyte cell number ( J:211773 )

♂

IMPC - TCP

small spleen ( J:211773 )

♂

IMPC - TCP

renal/urinary system

enlarged urinary bladder ( J:211773 )

♂

IMPC - TCP

skeleton

abnormal sternum morphology ( J:211773 )

♂

IMPC - TCP

decreased bone mineral content ( J:211773 )

♂

IMPC - TCP