All Phenotypes Gars1<em1(IMPC)Tcp> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gars1^em1(IMPC)Tcp
endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI:6156586

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gars1^em1(IMPC)Tcp/Gars1^em1(IMPC)Tcp	C57BL/6NCrl-Gars1^em1(IMPC)Tcp/Tcp	MGI:6262493
ht2	Gars1^em1(IMPC)Tcp/Gars1⁺	C57BL/6NCrl-Gars1^em1(IMPC)Tcp/Tcp	MGI:6461286

Allelic Composition	Gars1^em1(IMPC)Tcp/Gars1^em1(IMPC)Tcp
Genetic Background	C57BL/6NCrl-Gars1^em1(IMPC)Tcp/Tcp

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gars1^em1(IMPC)Tcp mutation (2 available); any Gars1 mutation (42 available)

Data Sources

IMPC Data for Gars1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Allelic Composition	Gars1^em1(IMPC)Tcp/Gars1⁺
Genetic Background	C57BL/6NCrl-Gars1^em1(IMPC)Tcp/Tcp

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gars1^em1(IMPC)Tcp mutation (2 available); any Gars1 mutation (42 available)

Data Sources

IMPC Data for Gars1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - TCP

cardiovascular system

enlarged heart ( J:211773 )

IMPC - TCP

digestive/alimentary system

abnormal stomach morphology ( J:211773 )

IMPC - TCP

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

IMPC - TCP

growth/size/body

enlarged heart ( J:211773 )

IMPC - TCP

enlarged urinary bladder ( J:211773 )

IMPC - TCP

hematopoietic system

small spleen ( J:211773 )

IMPC - TCP

homeostasis/metabolism

increased circulating triglyceride level ( J:211773 )

IMPC - TCP

immune system

small spleen ( J:211773 )

IMPC - TCP

integument

abnormal skin morphology ( J:211773 )

IMPC - TCP

renal/urinary system

enlarged urinary bladder ( J:211773 )

IMPC - TCP

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

IMPC - TCP

skeleton

abnormal sternum morphology ( J:211773 )

IMPC - TCP

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - TCP

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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