Phenotypes associated with this allele

• Allele Symbol: Nalcn^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6158472
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nalcn^em1(IMPC)Mbp/Nalcn^em1(IMPC)Mbp	C57BL/6N-Nalcn^em1(IMPC)Mbp/Ucd	MGI:6262965
ht2	Nalcn^em1(IMPC)Mbp/Nalcn^+	C57BL/6N-Nalcn^em1(IMPC)Mbp/Ucd	MGI:6262964

Genotype
MGI:6262965

hm1

• Allelic Composition: Nalcn^em1(IMPC)Mbp/Nalcn^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Nalcn^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Nalcn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

Genotype
MGI:6262964

ht2

• Allelic Composition: Nalcn^em1(IMPC)Mbp/Nalcn⁺
• Genetic Background: C57BL/6N-Nalcn^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Nalcn

cardiovascular system

hemorrhage ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

growth/size/body

enlarged spleen ( J:211773 )

♂

IMPC - UCD

hematopoietic system

increased neutrophil cell number ( J:211773 )

♂

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

immune system

increased neutrophil cell number ( J:211773 )

♂

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD