Phenotypes associated with this allele

• Allele Symbol: Zfp503^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6158506
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zfp503^em1(IMPC)Mbp/Zfp503^em1(IMPC)Mbp	C57BL/6N-Zfp503^em1(IMPC)Mbp/Ucd	MGI:6288839
ht2	Zfp503^em1(IMPC)Mbp/Zfp503^+	C57BL/6N-Zfp503^em1(IMPC)Mbp/Ucd	MGI:6394428

Genotype
MGI:6288839

hm1

• Allelic Composition: Zfp503^em1(IMPC)Mbp/Zfp503^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Zfp503^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Zfp503

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal placenta vasculature ( J:211773 )

♂

IMPC - UCD

craniofacial

abnormal head shape ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal embryo size ( J:211773 )

♂

IMPC - UCD

abnormal placenta morphology ( J:211773 )

♂

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

♂

IMPC - UCD

growth/size/body

abnormal head shape ( J:211773 )

IMPC - UCD

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal embryo size ( J:211773 )

♂

IMPC - UCD

microcephaly ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

vision/eye

anophthalmia ( J:211773 )

IMPC - UCD

Genotype
MGI:6394428

ht2

• Allelic Composition: Zfp503^em1(IMPC)Mbp/Zfp503⁺
• Genetic Background: C57BL/6N-Zfp503^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Zfp503

behavior/neurological

increased exploration in new environment ( J:211773 )

♂

IMPC - UCD

decreased grip strength ( J:211773 )

♀

IMPC - UCD

growth/size/body

enlarged kidney ( J:211773 )

♂

IMPC - UCD

hematopoietic system

increased basophil cell number ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

decreased circulating creatinine level ( J:211773 )

♂

IMPC - UCD

decreased circulating glucose level ( J:211773 )

♀

IMPC - UCD

edema ( J:211773 )

IMPC - UCD

immune system

increased basophil cell number ( J:211773 )

♀

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

IMPC - UCD

enlarged lymph nodes ( J:211773 )

IMPC - UCD

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

reproductive system

abnormal male genitalia morphology ( J:211773 )

IMPC - UCD

vision/eye

abnormal optic disk morphology ( J:211773 )

IMPC - UCD