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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dnmt3bem1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6158518
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dnmt3bem1(IMPC)Mbp/Dnmt3bem1(IMPC)Mbp C57BL/6N-Dnmt3bem1(IMPC)Mbp/Ucd MGI:6288429
ht2
 		Dnmt3bem1(IMPC)Mbp/Dnmt3b+ C57BL/6N-Dnmt3bem1(IMPC)Mbp/Ucd MGI:6262306


Genotype
MGI:6288429
hm1
Allelic
Composition		 Dnmt3bem1(IMPC)Mbp/Dnmt3bem1(IMPC)Mbp
Genetic
Background		 C57BL/6N-Dnmt3bem1(IMPC)Mbp/Ucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnmt3bem1(IMPC)Mbp mutation (1 available); any Dnmt3b mutation (52 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
hemorrhage ( J:211773 )
IMPC - UCD

craniofacial
cleft palate ( J:211773 )
IMPC - UCD

digestive/alimentary system
cleft palate ( J:211773 )
IMPC - UCD

embryo

growth/size/body
abnormal facial morphology ( J:211773 )
IMPC - UCD
cleft palate ( J:211773 )
IMPC - UCD
abnormal head shape ( J:211773 )
IMPC - UCD
embryonic growth retardation ( J:211773 )
IMPC - UCD
microcephaly ( J:211773 )
IMPC - UCD

homeostasis/metabolism
edema ( J:211773 )
IMPC - UCD

mortality/aging

vision/eye
microphthalmia ( J:211773 )
IMPC - UCD




Genotype
MGI:6262306
ht2
Allelic
Composition		 Dnmt3bem1(IMPC)Mbp/Dnmt3b+
Genetic
Background		 C57BL/6N-Dnmt3bem1(IMPC)Mbp/Ucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnmt3bem1(IMPC)Mbp mutation (1 available); any Dnmt3b mutation (52 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
hemorrhage ( J:211773 )
IMPC - UCD




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory