Analysis Tools
reproductive system
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• contain on average 1.5 times more cleaved caspase-3 positive tubules at 7 days post-partum compared to controls
• however, the number of apoptotic cells per tubule is similar to controls
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• display a Sertoli cell only syndrome
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small testis
(
J:261955
)
|
|
• at 5 months of age
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• at 5 months of age
|
|
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• all germ cells are lost during the first wave of spermatogenesis
|
azoospermia
(
J:261955
)
|
|
• loss of germ cells and absence of sperm in the epididymis
• Sertoli cell only syndrome develops by 23 days post-partum
• expression analysis indicates misregulation of some differentiation pathways during the first wave of spermatogenesis
|
|
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• cells do not leave the basement membrane and fail to develop past the leptotene stage
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endocrine/exocrine glands
|
|
• display a Sertoli cell only syndrome
|
small testis
(
J:261955
)
|
|
• at 5 months of age
|
|
|
• at 5 months of age
|
cellular
azoospermia
(
J:261955
)
|
|
• loss of germ cells and absence of sperm in the epididymis
• Sertoli cell only syndrome develops by 23 days post-partum
• expression analysis indicates misregulation of some differentiation pathways during the first wave of spermatogenesis
|
|
|
• cells do not leave the basement membrane and fail to develop past the leptotene stage
|
|
|
• contain on average 1.5 times more cleaved caspase-3 positive tubules at 7 days post-partum compared to controls
• however, the number of apoptotic cells per tubule is similar to controls
|
