Analysis Tools
homeostasis/metabolism
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• in doxycycline-treated male mice fed a high-fat diet
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• in glucose-stimulation in doxycycline-treated male mice and ex vivo islets
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• in doxycycline-treated male mice fed a high-fat diet
• however, insulin sensitivity is normal
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endocrine/exocrine glands
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• doxycycline-treated male mice exhibit a decrease in beta to alpha cell compared with control mice
• however, mice exhibit normal mean pancreas surface, islet size, individual beta-cell or alpha-cell mass
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• islet cells from doxycycline-treated male mice fed a high-fat diet exhibit improved cytosolic calcium fluxes and increased endoplasmic calcium stores
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growth/size/body
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N |
• doxycycline-treated male mice exhibit normal weight change in response to being fed a high-fat diet
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