Phenotypes associated with this allele

• Allele Symbol: Shoc1^tm2Rjpz
• Allele Name: targeted mutation 2, Roberto J Pezza
• Allele ID: MGI:6160879
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Shoc1^tm2Rjpz/Shoc1^tm2Rjpz	involves: C57BL/6N	MGI:6160905

Genotype
MGI:6160905

hm1

• Allelic Composition: Shoc1^tm2Rjpz/Shoc1^tm2Rjpz
• Genetic Background: involves: C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:262079 )

♀N • female gonad development is normal

azoospermia ( J:262079 )

♂ • lack of spermatozoa

abnormal chiasmata formation ( J:262079 )

♂ • reduced chiasma frequency in spermatocytes

abnormal chromosomal synapsis ( J:262079 )

♂ • in spermatocytes

arrest of male meiosis ( J:262079 )

♂ • at the end of prophase I with lagging chromosomes

increased male germ cell apoptosis ( J:262079 )

♂

small seminiferous tubules ( J:262079 )

♂

small testis ( J:262079 )

♂

decreased testis weight ( J:262079 )

♂

cellular

azoospermia ( J:262079 )

♂ • lack of spermatozoa

abnormal chiasmata formation ( J:262079 )

♂ • reduced chiasma frequency in spermatocytes

abnormal chromosomal synapsis ( J:262079 )

♂ • in spermatocytes

arrest of male meiosis ( J:262079 )

♂ • at the end of prophase I with lagging chromosomes

increased male germ cell apoptosis ( J:262079 )

♂

endocrine/exocrine glands

small seminiferous tubules ( J:262079 )

♂

small testis ( J:262079 )

♂

decreased testis weight ( J:262079 )

♂