Phenotypes associated with this allele

• Allele Symbol: Zdbf2^em1Dhbh
• Allele Name: endonuclease-mediated mutation 1, Deborah Bourchis
• Allele ID: MGI:6161219
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Zdbf2^em1Dhbh/Zdbf2^+	involves: C57BL/6J * DBA/2J	MGI:6163615

Genotype
MGI:6163615

ht1

• Allelic Composition: Zdbf2^em1Dhbh/Zdbf2⁺
• Genetic Background: involves: C57BL/6J * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:261327 )

• at 2 weeks of age in female and male mice when this allele is inherited paternally

decreased body weight ( J:261327 )

• when this allele is inherited paternally, more pronounced from the first to the fourth week of life and persisting at 30 weeks

• however, growth is normal when the allele is inherited maternally and prenatal growth is normal regardless of inheritance

cellular

abnormal DNA methylation ( J:261327 )

• methylation of the Zdbf2 somatic differentially methylated region is severely impaired when this allele is inherited paternally