Phenotypes associated with this allele

• Allele Symbol: Ints3^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:6161377
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ints3^em1(IMPC)J/Ints3^em1(IMPC)J	C57BL/6NJ-Ints3^em1(IMPC)J/Mmjax	MGI:6394313
ht2	Ints3^em1(IMPC)J/Ints3^+	C57BL/6NJ-Ints3^em1(IMPC)J/Mmjax	MGI:6288527

Genotype
MGI:6394313

hm1

• Allelic Composition: Ints3^em1(IMPC)J/Ints3^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Ints3^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Ints3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6288527

ht2

• Allelic Composition: Ints3^em1(IMPC)J/Ints3⁺
• Genetic Background: C57BL/6NJ-Ints3^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Ints3

behavior/neurological

increased aggression ( J:211773 )

♀

IMPC - JAX

increased grip strength ( J:211773 )

♀

IMPC - JAX

abnormal locomotor behavior ( J:211773 )

♀

IMPC - JAX

abnormal vocalization ( J:211773 )

IMPC - JAX

hematopoietic system

increased erythrocyte cell number ( J:211773 )

♂

IMPC - JAX

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - JAX

decreased mean corpuscular volume ( J:211773 )

♂

IMPC - JAX