Phenotypes associated with this allele

• Allele Symbol: Tg(Tie2-Gja5*,-EGFP)#Dach
• Allele Name: transgene insertion, Daniel J Chaston
• Allele ID: MGI:6162535
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Tie2-Gja5*,-EGFP)#Dach/0	involves: C57BL/6	MGI:6162554

Genotype
MGI:6162554

tg1

• Allelic Composition: Tg(Tie2-Gja5*,-EGFP)#Dach/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:218811 )

N • blood pressure, heart rate

abnormal blood vessel morphology ( J:218811 )

• of mesenteric resistance arteries

• significantly reduced active diameter

• myogenic response activated at significantly lower pressures

• reduced distensibility (increased wall component stiffness)

• significant residual tone in presence of supramaximal concentrations of vasodilator CGRP (calcitonin gene related peptide)

growth/size/body

growth/size/body region phenotype ( J:218811 )

N • body weight