growth/size/body
• both male and female homozygous mice exhibit decreased weight compared to controls
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reproductive system
• the outer dense fiber is either absent or improperly arranged
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• complete loss of the axoneme doublets in one side of the fibrous sheath
• disordered assembly of the '9 + 2' arrangement
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• abnormal or missing acrosomes
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• acrosomes are missing in some cases
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• the number of round spermatids was significantly decreased
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• the number of round spermatids was significantly decreased
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• the ectoplasmic specialization arrangement is disrupted
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• seminiferous tubules retained elongated spermatids among germ cells and did not release
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• male mice are completely sterile
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cellular
• the outer dense fiber is either absent or improperly arranged
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• complete loss of the axoneme doublets in one side of the fibrous sheath
• disordered assembly of the '9 + 2' arrangement
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• abnormal or missing acrosomes
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• acrosomes are missing in some cases
|
• the number of round spermatids was significantly decreased
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• the number of round spermatids was significantly decreased
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endocrine/exocrine glands
• the ectoplasmic specialization arrangement is disrupted
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