All Phenotypes Atp11a<tm1c(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Atp11a^{tm1c(KOMP)Wtsi}
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:6188633

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Atp11a^{tm1c(KOMP)Wtsi}/Atp11a^{tm1c(KOMP)Wtsi} Myf5^tm3(cre)Sor/Myf5⁺	involves: 129S4/SvJaeSor * C57BL/6JJcl * C57BL/6N	MGI:6188641

Allelic Composition	Atp11a^{tm1c(KOMP)Wtsi}/Atp11a^{tm1c(KOMP)Wtsi} Myf5^tm3(cre)Sor/Myf5⁺
Genetic Background	involves: 129S4/SvJaeSor * C57BL/6JJcl * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp11a^{tm1c(KOMP)Wtsi} mutation (0 available); any Atp11a mutation (54 available)
Myf5^tm3(cre)Sor mutation (1 available); any Myf5 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

muscle phenotype ( J:262981 )

N	• mice exhibit normal gross muscle morphology and function (grip strength and treadmill running tests)

abnormal myoblast differentiation ( J:262981 )

• isolated primary myoblasts form aberrantly enlarged syncytia upon differentiation

abnormal skeletal muscle regeneration ( J:262981 )

• abnormally fused myofibers following cardiotoxin-induced regeneration of the tibialis anterior muscle

cellular

abnormal myoblast differentiation ( J:262981 )

• isolated primary myoblasts form aberrantly enlarged syncytia upon differentiation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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