Phenotypes associated with this allele

• Allele Symbol: Itsn2^tm1Kure
• Allele Name: targeted mutation 1, Shigeo Kure
• Allele ID: MGI:6188888
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Itsn2^tm1Kure/Itsn2^tm1Kure	involves: C57BL/6	MGI:6188890

Genotype
MGI:6188890

hm1

• Allelic Composition: Itsn2^tm1Kure/Itsn2^tm1Kure
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

albuminuria ( J:262845 )

• from 12 to 48 hours after LPS injection

• however, levels return to normal at 60 hours

podocyte foot process effacement ( J:262845 )

• 48 hours after LPS injection due to delayed recovery compared with wild-type mice

homeostasis/metabolism

albuminuria ( J:262845 )

• from 12 to 48 hours after LPS injection

• however, levels return to normal at 60 hours

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
nephrotic syndrome		DOID:1184		J:262845