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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Sephs1tm1.2Dhat
targeted mutation 1.2, Dolph L Hatfield
MGI:6189534
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Sephs1tm1.2Dhat/Sephs1tm1.2Dhat involves: 129S4/SvJae * C57BL/6J * FVB/N MGI:6189552


Genotype
MGI:6189552
hm1
Allelic
Composition
Sephs1tm1.2Dhat/Sephs1tm1.2Dhat
Genetic
Background
involves: 129S4/SvJae * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sephs1tm1.2Dhat mutation (0 available); any Sephs1 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice are virtually resorbed by E14.5

embryo
• at E8.5 and E11.5
• 4-fold smaller than control mice at E11.5 with hypoblastic vestigial organs
• fused to the yolk sac

growth/size/body
• at E8.5 and E11.5
• 4-fold smaller than control mice at E11.5 with hypoblastic vestigial organs





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory