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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tssk4tm1.1Lgyu
targeted mutation 1.1, Long Yu
MGI:6191661
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tssk4tm1.1Lgyu/Tssk4tm1.1Lgyu B6.129(129S2)-Tssk4tm1.1Lgyu MGI:6191667


Genotype
MGI:6191667
hm1
Allelic
Composition		 Tssk4tm1.1Lgyu/Tssk4tm1.1Lgyu
Genetic
Background		 B6.129(129S2)-Tssk4tm1.1Lgyu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tssk4tm1.1Lgyu mutation (0 available); any Tssk4 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:263443 )
N
• female mice exhibit normal fertility
• male mice exhibit normal sexual behavior, testes and sperm count
abnormal sperm axoneme morphology ( J:263443 )
• one or more microtubule doublet is missing
abnormal sperm midpiece morphology ( J:263443 )
• bent in some sperm
• abnormally fused middle and principal pieces in some sperm
abnormal sperm principal piece morphology ( J:263443 )
• abnormally fused middle and principal pieces in some sperm
decreased litter size ( J:263443 )
• litter size is decreased 50% in male mice

cellular
abnormal sperm axoneme morphology ( J:263443 )
• one or more microtubule doublet is missing
abnormal sperm midpiece morphology ( J:263443 )
• bent in some sperm
• abnormally fused middle and principal pieces in some sperm
abnormal sperm principal piece morphology ( J:263443 )
• abnormally fused middle and principal pieces in some sperm




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory