All Phenotypes Klhl14<tm1.1Jyw> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Klhl14^tm1.1Jyw
targeted mutation 1.1, Ji-Yang Wang
MGI:6191749

Summary

2 genotypes

Allelic Composition	Klhl14^tm1.1Jyw/Klhl14^tm1.1Jyw
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klhl14^tm1.1Jyw mutation (0 available); any Klhl14 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• no mice are produced

Allelic Composition	Klhl14^tm1.1Jyw/Klhl14⁺
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klhl14^tm1.1Jyw mutation (0 available); any Klhl14 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:263511 )

N	• mice exhibit normal development, maturation and activation of spleen B-2 cells and basal serum immunoglobulin levels

decreased B-1a cell number ( J:263511 )

• in the peritoneal cavity

• however, B-1a cell survival and proliferation are normal

increased B-1b cell number ( J:263511 )

• in the peritoneal cavity

• however, B-1b cell survival and proliferation are normal

hematopoietic system

decreased B-1a cell number ( J:263511 )

• in the peritoneal cavity

• however, B-1a cell survival and proliferation are normal

increased B-1b cell number ( J:263511 )

• in the peritoneal cavity

• however, B-1b cell survival and proliferation are normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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