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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Klhl14tm1.1Jyw
targeted mutation 1.1, Ji-Yang Wang
MGI:6191749
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Klhl14tm1.1Jyw/Klhl14tm1.1Jyw involves: C57BL/6 MGI:6191768
ht2
Klhl14tm1.1Jyw/Klhl14+ involves: C57BL/6 MGI:6191769


Genotype
MGI:6191768
hm1
Allelic
Composition
Klhl14tm1.1Jyw/Klhl14tm1.1Jyw
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klhl14tm1.1Jyw mutation (0 available); any Klhl14 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6191769
ht2
Allelic
Composition
Klhl14tm1.1Jyw/Klhl14+
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klhl14tm1.1Jyw mutation (0 available); any Klhl14 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• mice exhibit normal development, maturation and activation of spleen B-2 cells and basal serum immunoglobulin levels
• in the peritoneal cavity
• however, B-1a cell survival and proliferation are normal
• in the peritoneal cavity
• however, B-1b cell survival and proliferation are normal

hematopoietic system
• in the peritoneal cavity
• however, B-1a cell survival and proliferation are normal
• in the peritoneal cavity
• however, B-1b cell survival and proliferation are normal





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory