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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Myh6-Mir30c-1)AEec
transgene insertion A, Esther E Creemers
MGI:6192033
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Myh6-Mir30c-1)AEec/0 involves: C57BL/6JOlaHsd * FVB/N MGI:6192037


Genotype
MGI:6192037
tg1
Allelic
Composition		 Tg(Myh6-Mir30c-1)AEec/0
Genetic
Background		 involves: C57BL/6JOlaHsd * FVB/N
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:216095 )
• 50% lethality at 37 weeks of age

cardiovascular system
dilated heart ventricle ( J:216095 )
• end-stage failing heart shows ventricular dilation
cardiac interstitial fibrosis ( J:216095 )
• seen at end-stage of the disease
dilated cardiomyopathy ( J:216095 )
• mice develop a severely dilated cardiomyopathy after 20 weeks of age

muscle
dilated cardiomyopathy ( J:216095 )
• mice develop a severely dilated cardiomyopathy after 20 weeks of age

cellular
cardiac interstitial fibrosis ( J:216095 )
• seen at end-stage of the disease




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory