Phenotypes associated with this allele

• Allele Symbol: Cftr^em3Cwr
• Allele Name: endonuclease-mediated mutation 3, Case Western Reserve University
• Allele ID: MGI:6192450
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cftr^em3Cwr/Cftr^em3Cwr	C57BL/6J-Cftr^em3Cwr/Cwr	MGI:6192451

Genotype
MGI:6192451

hm1

• Allelic Composition: Cftr^em3Cwr/Cftr^em3Cwr
• Genetic Background: C57BL/6J-Cftr^em3Cwr/Cwr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:262928 )

• reduction in survival rate, with a 33% survival at 44 days of age

premature death ( J:262928 )

• 67% of mice die by P44

growth/size/body

decreased body weight ( J:262928 )

• mice exhibit reduced weight from 10-40 days of age

decreased body length ( J:262928 )

• 6 week old mice are reduced in length

digestive/alimentary system

intestinal obstruction ( J:262928 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cystic fibrosis		DOID:1485	OMIM:219700	J:262928