Phenotypes associated with this allele

• Allele Symbol: Trdmt1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6195686
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trdmt1^tm1b(EUCOMM)Hmgu/Trdmt1^tm1b(EUCOMM)Hmgu	C57BL/6N-Trdmt1^tm1b(EUCOMM)Hmgu/H	MGI:6408740
ht2	Trdmt1^tm1b(EUCOMM)Hmgu/Trdmt1^+	C57BL/6N-Trdmt1^tm1b(EUCOMM)Hmgu/H	MGI:6461767

Genotype
MGI:6408740

hm1

• Allelic Composition: Trdmt1^{tm1b(EUCOMM)Hmgu}/Trdmt1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Trdmt1^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0748_3_C12

Data Sources

IMPC Data for Trdmt1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - HAR

hyperactivity ( J:211773 )

♂

IMPC - HAR

hematopoietic system

decreased mean platelet volume ( J:211773 )

♀

IMPC - HAR

vision/eye

abnormal retina morphology ( J:211773 )

IMPC - HAR

Genotype
MGI:6461767

ht2

• Allelic Composition: Trdmt1^{tm1b(EUCOMM)Hmgu}/Trdmt1⁺
• Genetic Background: C57BL/6N-Trdmt1^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0748_3_C12

Data Sources

IMPC Data for Trdmt1

cardiovascular system

prolonged PR interval ( J:211773 )

♀

IMPC - HAR

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - HAR