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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Abcc6tm1c(EUCOMM)Wtsi
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:6195711
Summary 12 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Speer6-ps1Tg(Alb-cre)21Mgn/?
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn MGI:6241503
cn2
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Speer6-ps1Tg(Alb-cre)21Mgn/?
Tg(Cdx1-cre)23Kem/?
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn Tg(Cdx1-cre)23Kem MGI:6241505
cn3
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(Cdh16-cre)91Igr/?
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(Cdh16-cre)91Igr MGI:6241512
cn4
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(Cdh5-cre)7Mlia/?
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(Cdh5-cre)7Mlia MGI:6241514
cn5
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(CMV-cre)1Cgn/?
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(CMV-cre)1Cgn MGI:6241496
cn6
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(Fabp4-cre)1Rev/?
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(Fabp4-cre)1Rev MGI:6241516
cn7
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(Pdgfrb-cre)35Vli/?
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(Pdgfrb-cre)35Vli MGI:6241519
cn8
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(Tagln-cre)1Her/?
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(Tagln-cre)1Her MGI:6241522
cn9
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
E2f1Tg(Wnt1-cre)2Sor/?
B6.Cg-E2f1Tg(Wnt1-cre)2Sor Abcc6tm1c(EUCOMM)Wtsi MGI:6241498
cn10
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
E2f1Tg(Wnt1-cre)2Sor/?
Speer6-ps1Tg(Alb-cre)21Mgn/?
B6.Cg-E2f1Tg(Wnt1-cre)2Sor Abcc6tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn MGI:6241501
cn11
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Pax7tm1(cre)Mrc/?
B6.Cg-Pax7tm1(cre)Mrc Abcc6tm1c(EUCOMM)Wtsi MGI:6241508
cn12
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Ptprctm1(cre)Medv/?
B6.Cg-Ptprctm1(cre)Medv Abcc6tm1c(EUCOMM)Wtsi MGI:6241510


Genotype
MGI:6241503
cn1
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Speer6-ps1Tg(Alb-cre)21Mgn/?
Genetic
Background
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism

integument
• calcification of the fibrous capsule surrounding the muzzle vibrissae is not observed at 20 weeks of age, however, at one year of age, some calcification is present

growth/size/body

craniofacial




Genotype
MGI:6241505
cn2
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Speer6-ps1Tg(Alb-cre)21Mgn/?
Tg(Cdx1-cre)23Kem/?
Genetic
Background
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn Tg(Cdx1-cre)23Kem
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
Tg(Cdx1-cre)23Kem mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism

integument
• calcification of the fibrous capsule surrounding the muzzle vibrissae is not observed at 20 weeks of age, however, at one year of age, some calcification is present

growth/size/body

craniofacial




Genotype
MGI:6241512
cn3
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(Cdh16-cre)91Igr/?
Genetic
Background
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(Cdh16-cre)91Igr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
Tg(Cdh16-cre)91Igr mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
N
• no calcification occurs in the fibrous capsule surrounding the muzzle vibrissae




Genotype
MGI:6241514
cn4
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(Cdh5-cre)7Mlia/?
Genetic
Background
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(Cdh5-cre)7Mlia
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
Tg(Cdh5-cre)7Mlia mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
N
• no calcification occurs in the fibrous capsule surrounding the muzzle vibrissae




Genotype
MGI:6241496
cn5
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(CMV-cre)1Cgn/?
Genetic
Background
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(CMV-cre)1Cgn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
Tg(CMV-cre)1Cgn mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism

integument
• calcification of the fibrous capsule surrounding the muzzle vibrissae occurs at 20 weeks of age

growth/size/body

craniofacial




Genotype
MGI:6241516
cn6
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(Fabp4-cre)1Rev/?
Genetic
Background
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(Fabp4-cre)1Rev
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
Tg(Fabp4-cre)1Rev mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
N
• no calcification occurs in the fibrous capsule surrounding the muzzle vibrissae




Genotype
MGI:6241519
cn7
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(Pdgfrb-cre)35Vli/?
Genetic
Background
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(Pdgfrb-cre)35Vli
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
Tg(Pdgfrb-cre)35Vli mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
N
• no calcification occurs in the fibrous capsule surrounding the muzzle vibrissae




Genotype
MGI:6241522
cn8
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Tg(Tagln-cre)1Her/?
Genetic
Background
B6.Cg-Abcc6tm1c(EUCOMM)Wtsi Tg(Tagln-cre)1Her
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
Tg(Tagln-cre)1Her mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
N
• no calcification occurs in the fibrous capsule surrounding the muzzle vibrissae




Genotype
MGI:6241498
cn9
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
E2f1Tg(Wnt1-cre)2Sor/?
Genetic
Background
B6.Cg-E2f1Tg(Wnt1-cre)2Sor Abcc6tm1c(EUCOMM)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
E2f1Tg(Wnt1-cre)2Sor mutation (2 available); any E2f1 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism

integument
• 1 out of 22 mice exhibit mild calcification of the fibrous capsule surrounding the muzzle vibrissae occurs at 20 weeks of age
• at one year of age, the calcification phenotype shows reduced penetrance and variable expression

growth/size/body

craniofacial




Genotype
MGI:6241501
cn10
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
E2f1Tg(Wnt1-cre)2Sor/?
Speer6-ps1Tg(Alb-cre)21Mgn/?
Genetic
Background
B6.Cg-E2f1Tg(Wnt1-cre)2Sor Abcc6tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
E2f1Tg(Wnt1-cre)2Sor mutation (2 available); any E2f1 mutation (28 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism

integument
• 5 out of 13 mice exhibit calcification of the fibrous capsule surrounding the muzzle vibrissae occurs at 20 weeks of age

growth/size/body

craniofacial




Genotype
MGI:6241508
cn11
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Pax7tm1(cre)Mrc/?
Genetic
Background
B6.Cg-Pax7tm1(cre)Mrc Abcc6tm1c(EUCOMM)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
Pax7tm1(cre)Mrc mutation (2 available); any Pax7 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
N
• no calcification occurs in the fibrous capsule surrounding the muzzle vibrissae




Genotype
MGI:6241510
cn12
Allelic
Composition
Abcc6tm1c(EUCOMM)Wtsi/Abcc6tm1c(EUCOMM)Wtsi
Ptprctm1(cre)Medv/?
Genetic
Background
B6.Cg-Ptprctm1(cre)Medv Abcc6tm1c(EUCOMM)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1c(EUCOMM)Wtsi mutation (1 available); any Abcc6 mutation (76 available)
Ptprctm1(cre)Medv mutation (0 available); any Ptprc mutation (189 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
N
• no calcification occurs in the fibrous capsule surrounding the muzzle vibrissae





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory