homeostasis/metabolism
• mice lose more than 10 times the volume of blood lost by wild-type controls after tail-clip
|
• activated partial thromboplastin time is prolonged in 8 week old mice
• however, average prothrombin time is normal
|
• survival rate is decreased in the 2 days after the tail-clip challenge
|
mortality/aging
• survival rate is decreased in the 2 days after the tail-clip challenge
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
hemophilia B | DOID:12259 |
OMIM:306900 |
J:262204 |