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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Scgb3a2tm1.1Shk
targeted mutation 1.1, Shioko Kimura
MGI:6196554
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Scgb3a2tm1.1Shk/Scgb3a2tm1.1Shk B6N.Cg-Scgb3a2tm1.1Shk MGI:6500971
hm2
 		Scgb3a2tm1.1Shk/Scgb3a2tm1.1Shk B6NCr.Cg-Scgb3a2tm1.1Shk MGI:6196581
hm3
 		Scgb3a2tm1.1Shk/Scgb3a2tm1.1Shk involves: 129S4/SvJae * C57BL/6J * C57BL/6N MGI:6500969
hm4
 		Scgb3a2tm1.1Shk/Scgb3a2tm1.1Shk involves: 129S4/SvJae * C57BL/6J * C57BL/6NCr * FVB/N MGI:6196579


Genotype
MGI:6500971
hm1
Allelic
Composition		 Scgb3a2tm1.1Shk/Scgb3a2tm1.1Shk
Genetic
Background		 B6N.Cg-Scgb3a2tm1.1Shk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scgb3a2tm1.1Shk mutation (0 available); any Scgb3a2 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular

respiratory system




Genotype
MGI:6196581
hm2
Allelic
Composition		 Scgb3a2tm1.1Shk/Scgb3a2tm1.1Shk
Genetic
Background		 B6NCr.Cg-Scgb3a2tm1.1Shk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scgb3a2tm1.1Shk mutation (0 available); any Scgb3a2 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:263506 )
N
• Background Sensitivity: unlike mice on a mixed background, mice on a congenic C57BL/6NCr background exhibit normal response to ovalbumin exposure




Genotype
MGI:6500969
hm3
Allelic
Composition		 Scgb3a2tm1.1Shk/Scgb3a2tm1.1Shk
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scgb3a2tm1.1Shk mutation (0 available); any Scgb3a2 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
respiratory system phenotype ( J:276140 )
• mice exhibit normal average pulmonary neuroepithelial body (NEB) area




Genotype
MGI:6196579
hm4
Allelic
Composition		 Scgb3a2tm1.1Shk/Scgb3a2tm1.1Shk
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J * C57BL/6NCr * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scgb3a2tm1.1Shk mutation (0 available); any Scgb3a2 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased susceptibility to injury ( J:263506 )
• Background Sensitivity: mice on a mixed background exposed to ovalbumin exhibit lower incidence and grading with reduced inflammatory cells in bronchoalveolar lavage fluid compared with wild-type mice unlike mice on a congenic C57BL/6NCr background




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory