Phenotypes associated with this allele

• Allele Symbol: Creg1^em1Yal
• Allele Name: endonuclease-mediated mutation 1, Ya-Ling Han
• Allele ID: MGI:6196852
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Creg1^em1Yal/Creg1^em1Yal Speer6-ps1^Tg(Alb-cre)21Mgn/Speer6-ps1^+	involves: C57BL/6 * DBA	MGI:6196883

Genotype
MGI:6196883

cn1

• Allelic Composition: Creg1^em1Yal/Creg1^em1Yal; Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺
• Genetic Background: involves: C57BL/6 * DBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal circulating enzyme level ( J:263073 )

increased circulating alanine transaminase level ( J:263073 )

• when fed a high fat diet

increased circulating alkaline phosphatase level ( J:263073 )

• when fed a high fat diet

increased circulating aspartate transaminase level ( J:263073 )

• when fed a high fat diet

abnormal glucose homeostasis ( J:263073 )

increased fasting circulating glucose level ( J:263073 )

• when fed a high fat diet

increased circulating insulin level ( J:263073 )

• fasted levels when mice are fed a high fat diet

impaired glucose tolerance ( J:263073 )

• when fed a high fat diet

decreased glycogen level ( J:263073 )

• when fed a high fat diet

insulin resistance ( J:263073 )

• when fed a high fat diet

abnormal lipid homeostasis ( J:263073 )

increased liver cholesterol level ( J:263073 )

• when fed a high fat diet

increased liver free fatty acids level ( J:263073 )

• nonesterified when fed a high fat diet

liver/biliary system

increased liver weight ( J:263073 )

• when fed a high fat diet

increased liver cholesterol level ( J:263073 )

• when fed a high fat diet

increased liver free fatty acids level ( J:263073 )

• nonesterified when fed a high fat diet

decreased susceptibility to diet-induced hepatic steatosis ( J:263073 )

• when fed a high fat diet

growth/size/body

increased body weight ( J:263073 )

• when fed a high fat diet

increased liver weight ( J:263073 )

• when fed a high fat diet